Two brothers Connor (Sean Patrick Flanery) and Murphy MacManus (Norman Reedus) try to find the killer of their beloved priest and prove their innocence.
The film is the sequel to The Boondock Saints released in 1999. In the second part, brothers Connor (Sean Patrick Flanery) and Murphy MacManus (Norman Reedus) are leading a quiet life with their father in a sheep farm in Ireland.
One day, they get to know from their uncle that their beloved priest has been murdered and they (MacManus brothers) have been framed in the crime. Now, Connor and Murphy must return to Boston to prove their innocence as well as to find the killer. The task is difficult but they do not have any other option left.